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Joseph Lachance
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A recent bottleneck of Y chromosome diversity coincides with a global change in culture
M Karmin, L Saag, M Vicente, MA Wilson Sayres, M Järve, UG Talas, ...
Genome Research 25, 459-466, 2015
4762015
Genomic analyses inform on migration events during the peopling of Eurasia
L Pagani, DJ Lawson, E Jagoda, A Mörseburg, A Eriksson, M Mitt, ...
Nature 538 (7624), 238-242, 2016
4562016
Evolutionary history and adaptation from high-coverage whole-genome sequences of diverse African hunter-gatherers
J Lachance, B Vernot, CC Elbers, B Ferwerda, A Froment, JM Bodo, ...
Cell 150 (3), 457-469, 2012
3622012
SNP ascertainment bias in population genetic analyses: why it is important, and how to correct it
J Lachance, SA Tishkoff
Bioessays 35 (9), 780-786, 2013
3422013
The genetic prehistory of southern Africa
JK Pickrell, N Patterson, C Barbieri, F Berthold, L Gerlach, T Güldemann, ...
Nature Communications 3, 1143, 2012
3202012
Genetic disease risks can be misestimated across global populations
MS Kim, KP Patel, AK Teng, AJ Berens, J Lachance
Genome biology 19, 1-14, 2018
1722018
Model-based analyses of whole-genome data reveal a complex evolutionary history involving archaic introgression in Central African Pygmies.
PH Hsieh, AE Woerner, JD Wall, J Lachance, SA Tishkoff, RN Gutenkunst, ...
Genome Research 26 (3), 291, 2016
1212016
Phylogeny estimation by integration over isolation with migration models
J Hey, Y Chung, A Sethuraman, J Lachance, S Tishkoff, VC Sousa, ...
Molecular biology and evolution 35 (11), 2805-2818, 2018
1152018
The genetics of sex chromosomes: evolution and implications for hybrid incompatibility
NA Johnson, J Lachance
Annals of the New York Academy of Sciences 1256 (1), E1-E22, 2012
1072012
Population genomics of human adaptation
J Lachance, SA Tishkoff
Annual Review of Ecology, Evolution, and Systematics 44, 123-143, 2013
1022013
Whole genome sequence analyses of Western Central African Pygmy hunter-gatherers reveal a complex demographic history and identify candidate genes under positive natural selection
PH Hsieh, KR Veeramah, J Lachance, SA Tishkoff, JD Wall, MF Hammer, ...
Genome Research 26 (3), 279, 2016
672016
Biased gene conversion skews allele frequencies in human populations, increasing the disease burden of recessive alleles
J Lachance, SA Tishkoff
The American Journal of Human Genetics 95 (4), 408-420, 2014
632014
Genetic hitchhiking and population bottlenecks contribute to prostate cancer disparities in men of African descent
J Lachance, AJ Berens, MEB Hansen, AK Teng, SA Tishkoff, TR Rebbeck
Cancer research 78 (9), 2432-2443, 2018
612018
Apparent variation in Neanderthal admixture among African populations is consistent with gene flow from non-African populations
S Wang, J Lachance, SA Tishkoff, J Hey, J Xing
Genome biology and evolution 5 (11), 2075-2081, 2013
472013
Disease-associated alleles in genome-wide association studies are enriched for derived low frequency alleles relative to HapMap and neutral expectations
J Lachance
BMC medical genomics 3 (1), 57, 2010
372010
The genomic health of ancient hominins
AJ Berens, TL Cooper, J Lachance
Human biology 89 (1), 7-19, 2017
362017
X‐autosome incompatibilities in Drosophila melanogaster: tests of Haldane's rule and geographical patterns within species
J Lachance, JR True
Evolution 64 (10), 3035-3046, 2010
352010
Long-term adaptation of epistatic genetic networks
R Yukilevich, J Lachance, F Aoki, JR True
Evolution 62 (9), 2215-2235, 2008
352008
Evidence for positive selection on recent human transposable element insertions
L Rishishwar, L Wang, J Wang, VY Soojin, J Lachance, IK Jordan
Gene 675, 69-79, 2018
342018
Detecting selection-induced departures from Hardy-Weinberg proportions
J Lachance
Genetics Selection Evolution 41, 1-6, 2009
332009
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Artiklar 1–20