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Vinee Purohit
Vinee Purohit
Harvard Medical School/Brigham and Women's Hospital/Broad Institute
Verifierad e-postadress på broadinstitute.org
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Cysteine depletion induces pancreatic tumor ferroptosis in mice
MA Badgley, DM Kremer, HC Maurer, KE DelGiorno, HJ Lee, V Purohit, ...
Science 368 (6486), 85-89, 2020
8042020
MUC1 and HIF-1alpha signaling crosstalk induces anabolic glucose metabolism to impart gemcitabine resistance to pancreatic cancer
SK Shukla, V Purohit, K Mehla, V Gunda, NV Chaika, E Vernucci, RJ King, ...
Cancer cell 32 (1), 71-87. e7, 2017
4592017
Metabolic reprogramming induced by ketone bodies diminishes pancreatic cancer cachexia
SK Shukla, T Gebregiworgis, V Purohit, NV Chaika, V Gunda, ...
Cancer & metabolism 2, 1-19, 2014
2462014
Graviola: a novel promising natural-derived drug that inhibits tumorigenicity and metastasis of pancreatic cancer cells in vitro and in vivo through altering cell metabolism
MP Torres, S Rachagani, V Purohit, P Pandey, S Joshi, ED Moore, ...
Cancer letters 323 (1), 29-40, 2012
2432012
MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer
NV Chaika, T Gebregiworgis, ME Lewallen, V Purohit, P Radhakrishnan, ...
Proceedings of the National Academy of Sciences 109 (34), 13787-13792, 2012
2272012
Differential expression of metabolic genes in tumor and stromal components of primary and metastatic loci in pancreatic adenocarcinoma
NV Chaika, F Yu, V Purohit, K Mehla, AJ Lazenby, D DiMaio, ...
PloS one 7 (3), e32996, 2012
1082012
Active YAP promotes pancreatic cancer cell motility, invasion and tumorigenesis in a mitotic phosphorylation-dependent manner through LPAR3
S Yang, L Zhang, V Purohit, SK Shukla, X Chen, F Yu, K Fu, Y Chen, ...
Oncotarget 6 (34), 36019, 2015
1042015
Metabolic regulation of redox balance in cancer
V Purohit, DM Simeone, CA Lyssiotis
Cancers 11 (7), 955, 2019
942019
High-content fluorescence imaging with the metabolic flux assay reveals insights into mitochondrial properties and functions
AC Little, I Kovalenko, LE Goo, HS Hong, SA Kerk, JA Yates, V Purohit, ...
Communications biology 3 (1), 271, 2020
562020
MUC1 facilitates metabolomic reprogramming in triple-negative breast cancer
G Goode, V Gunda, NV Chaika, V Purohit, F Yu, PK Singh
PloS one 12 (5), e0176820, 2017
452017
Systems-based approaches to study immunometabolism
V Purohit, A Wagner, N Yosef, VK Kuchroo
Cellular & molecular immunology 19 (3), 409-420, 2022
292022
Insights into gemcitabine resistance and the potential for therapeutic monitoring
T Gebregiworgis, F Bhinderwala, V Purohit, NV Chaika, PK Singh, ...
Metabolomics 14, 1-7, 2018
292018
Glucose limitation alters glutamine metabolism in MUC1-overexpressing pancreatic cancer cells
T Gebregiworgis, V Purohit, SK Shukla, S Tadros, NV Chaika, J Abrego, ...
Journal of proteome research 16 (10), 3536-3546, 2017
292017
ATDC binds to KEAP1 to drive NRF2-mediated tumorigenesis and chemoresistance in pancreatic cancer
V Purohit, L Wang, H Yang, J Li, GM Ney, ER Gumkowski, AJ Vaidya, ...
Genes & Development, 2021
252021
Tim-3 adapter protein Bat3 acts as an endogenous regulator of tolerogenic dendritic cell function
R Tang, N Acharya, A Subramanian, V Purohit, M Tabaka, Y Hou, D He, ...
Science immunology 7 (69), eabm0631, 2022
222022
ATDC is required for the initiation of KRAS-induced pancreatic tumorigenesis
L Wang, H Yang, A Zamperone, D Diolaiti, PL Palmbos, EV Abel, ...
Genes & Development 33 (11-12), 641-655, 2019
222019
Correction: MUC1 facilitates metabolomic reprogramming in triple-negative breast cancer
G Goode, V Gunda, NV Chaika, V Purohit, F Yu, PK Singh
Plos one 12 (6), e0179098, 2017
42017
Graviola:-Novel promising natural derived drug that inhibits tumorigenicity and metastasis of pancreatic cancer cell in vitro and in vivo through alternating cell metabolism …
MP Torves, S Rachagani, V Purohit, P Pandey, S Joshi, ED Moore, ...
Cancer cell, Letters 323, 29-40, 2012
32012
Induction of pancreatic tumor-selective ferroptosis through modulation of cystine import
MA Badgley, D Kremer, HC Maurer, KE DelGiorno, HJ Lee, V Purohit, ...
BioRxiv, 827972, 2019
22019
Möglichkeiten und Grenzen der ketogenen Ernährung in der Krebstherapie
U Kämmerer, RJ Klement
Zeitschrift für Orthomolekulare Medizin 15 (02), 20-24, 2017
22017
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Artiklar 1–20