Philip Anton van der Merwe

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Omer DushekProfessor, University of OxfordVerified email at path.ox.ac.uk
E Yvonne JonesThe Sir Andrew McMichael Professor of Structural Immunology, University of OxfordVerified email at strubi.ox.ac.uk
Michael DustinUniversity of OxfordVerified email at kennedy.ox.ac.uk
David StuartMRC Professor of Structural Biology Oxford University, Diamond Light SourceVerified email at strubi.ox.ac.uk
Elizabeth DaviesOSUSURGERY, The Ohio State UniversityVerified email at osu.edu
Kaushik ChoudhuriAssistant Professor at University of Michigan Medical SchoolVerified email at med.umich.edu
Dr Ji-Li ChenUniversity of OxfordVerified email at imm.ox.ac.uk
Philip MainiProfessor of Mathematical BiologyVerified email at maths.ox.ac.uk
Daniel CoombsProfessor, Mathematics, University of British ColumbiaVerified email at math.ubc.ca
Karl HarlosOxford UniversityVerified email at strubi.ox.ac.uk
Michael G TomlinsonAssociate Professor/Reader, School of Biosciences, University of BirminghamVerified email at bham.ac.uk
Linda WooldridgeChair in Translational ImmunologyVerified email at bristol.ac.uk
Jun AllardUniversity of California, IrvineVerified email at uci.edu
Iain D CampbellProfessor of Structural Biology, Department of Biochemistry, University of Oxford, OX1 3QU, UKVerified email at bioch.ox.ac.uk
A. Radu AricescuMRC Laboratory of Molecular Biology, Cambridge and University of OxfordVerified email at mrc-lmb.cam.ac.uk
Alexandre M CarmoIBMCVerified email at ibmc.up.pt
Vahid ShahrezaeiDepartment of Mathematics, Imperial College LondonVerified email at imperial.ac.uk
David ColeHonorary Professor, Cardiff UniversityVerified email at cf.ac.uk

Philip Anton van der Merwe

Professor of Molecular Immunology, University of Oxford

Verified email at path.ox.ac.uk - Homepage

Immunology


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The leucocyte antigen factsbook AN Barclay, MH Brown, SKAKA Law, AJ McKnight, MG Tomlinson, ... Elsevier, 1997	894	1997
A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts ML Dustin, MW Olszowy, AD Holdorf, J Li, S Bromley, N Desai, P Widder, ... Cell 94 (5), 667-677, 1998	867	1998
The interaction properties of costimulatory molecules revisited AV Collins, DW Brodie, RJC Gilbert, A Iaboni, R Manso-Sancho, B Walse, ... Immunity 17 (2), 201-210, 2002	860	2002
Production of soluble αβ T‐cell receptor heterodimers suitable for biophysical analysis of ligand binding BE Willcox, GF Gao, JR Wyer, CA O'callaghan, BK Jakobsen, JM Boulter, ... Protein Science 8 (11), 2418-2423, 1999	729	1999
CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics PA van der Merwe, DL Bodian, S Daenke, P Linsley, SJ Davis The Journal of experimental medicine 185 (3), 393-404, 1997	708	1997
Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G M Shiroishi, K Tsumoto, K Amano, Y Shirakihara, M Colonna, VM Braud, ... Proceedings of the National Academy of Sciences 100 (15), 8856-8861, 2003	651	2003
Molecular interactions mediating T cell antigen recognition PA van der Merwe, SJ Davis Annual review of immunology 21 (1), 659-684, 2003	622	2003
The kinetic-segregation model: TCR triggering and beyond SJ Davis, PA Van Der Merwe Nature immunology 7 (8), 803-809, 2006	583	2006
Mechanisms for T cell receptor triggering PA Van Der Merwe, O Dushek Nature Reviews Immunology 11 (1), 47-55, 2011	571	2011
2B4, the natural killer and T cell immunoglobulin superfamily surface protein, is a ligand for CD48 MH Brown, K Boles, P Anton Van der Merwe, V Kumar, PA Mathew, ... The Journal of experimental medicine 188 (11), 2083-2090, 1998	513	1998
The structure and ligand interactions of CD2: implications for T-cell function SJ Davis, PA Van Der Merwe Immunology today 17 (4), 177-187, 1996	505	1996
T-cell receptor triggering is critically dependent on the dimensions of its peptide-MHC ligand K Choudhuri, D Wiseman, MH Brown, K Gould, PA van der Merwe Nature 436 (7050), 578-582, 2005	397	2005
TCR binding to peptide-MHC stabilizes a flexible recognition interface BE Willcox, GF Gao, JR Wyer, JE Ladbury, JI Bell, BK Jakobsen, ... Immunity 10 (3), 357-365, 1999	380	1999
Survival of FimH-expressing enterobacteria in macrophages relies on glycolipid traffic DM Baorto, Z Gao, R Malaviya, ML Dustin, A van der Merwe, DM Lublin, ... Nature 389 (6651), 636-639, 1997	370	1997
The mast cell tumor necrosis factor α response to FimH-expressing Escherichia coli is mediated by the glycosylphosphatidylinositol-anchored molecule CD48 R Malaviya, Z Gao, K Thankavel, PA van der Merwe, SN Abraham Proceedings of the National Academy of Sciences 96 (14), 8110-8115, 1999	308	1999
The nature of molecular recognition by T cells SJ Davis, S Ikemizu, EJ Evans, L Fugger, TR Bakker, PA van der Merwe Nature immunology 4 (3), 217-224, 2003	305	2003
CDR3 loop flexibility contributes to the degeneracy of TCR recognition JB Reiser, C Darnault, C Grégoire, T Mosser, G Mazza, A Kearney, ... Nature immunology 4 (3), 241-247, 2003	305	2003
Structural and kinetic basis for heightened immunogenicity of T cell vaccines JL Chen, G Stewart-Jones, G Bossi, NM Lissin, L Wooldridge, EML Choi, ... The Journal of experimental medicine 201 (8), 1243-1255, 2005	298	2005
Siglecs: a family of sialic-acid binding lectins PR Crocker, EA Clark, M Filbin, S Gordon, Y Jones, JH Kehrl, S Kelm, ... Glycobiology 8 (2), v-vi, 1998	294	1998
Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition PA van der Merwe, SJ Davis, AS Shaw, ML Dustin Semin. Immunol. 12 (5), 21, 2000	288	2000

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