G Greg Wang, PHD & Professor
G Greg Wang, PHD & Professor
Department of Pharmacology and Cancer Biology, Duke Cancer Institute, Duke University
Verified email at - Homepage
Cited by
Cited by
Covalent histone modifications—miswritten, misinterpreted and mis-erased in human cancers
P Chi, CD Allis, GG Wang
Nature reviews cancer 10 (7), 457-469, 2010
Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6
H Häcker, V Redecke, B Blagoev, I Kratchmarova, LC Hsu, GG Wang, ...
Nature 439 (7073), 204-207, 2006
Chromatin remodeling and cancer, Part I: Covalent histone modifications
GG Wang, CD Allis, P Chi
Trends in molecular medicine 13 (9), 363-372, 2007
An orally bioavailable chemical probe of the lysine methyltransferases EZH2 and EZH1
KD Konze, A Ma, F Li, D Barsyte-Lovejoy, T Parton, CJ MacNevin, F Liu, ...
ACS chemical biology 8 (6), 1324-1334, 2013
NUP98–NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis
GG Wang, L Cai, MP Pasillas, MP Kamps
Nature cell biology 9 (7), 804-812, 2007
Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger
GG Wang, J Song, Z Wang, HL Dormann, F Casadio, H Li, JL Luo, ...
Nature 459 (7248), 847-851, 2009
Quantitative production of macrophages or neutrophils ex vivo using conditional Hoxb8
GG Wang, KR Calvo, MP Pasillas, DB Sykes, H Häcker, MP Kamps
Nature methods 3 (4), 287-293, 2006
Chromatin remodeling and cancer, Part II: ATP-dependent chromatin remodeling
GG Wang, CD Allis, P Chi
Trends in molecular medicine 13 (9), 373-380, 2007
An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting
L Cai, SB Rothbart, R Lu, B Xu, WY Chen, A Tripathy, S Rockowitz, ...
Molecular cell 49 (3), 571-582, 2013
Structural basis for DNMT3A-mediated de novo DNA methylation
ZM Zhang, R Lu, P Wang, Y Yu, D Chen, L Gao, S Liu, D Ji, SB Rothbart, ...
Nature 554 (7692), 387-391, 2018
PHD fingers in human diseases: disorders arising from misinterpreting epigenetic marks
LA Baker, CD Allis, GG Wang
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 647 (1 …, 2008
Multiple interactions recruit MLL1 and MLL1 fusion proteins to the HOXA9 locus in leukemogenesis
TA Milne, J Kim, GG Wang, SC Stadler, V Basrur, SJ Whitcomb, Z Wang, ...
Molecular cell 38 (6), 853-863, 2010
Phase separation drives aberrant chromatin looping and cancer development
JH Ahn, ES Davis, TA Daugird, S Zhao, IY Quiroga, H Uryu, J Li, AJ Storey, ...
Nature 595 (7868), 591-595, 2021
Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression
Z Wang, J Song, TA Milne, GG Wang, H Li, CD Allis, DJ Patel
Cell 141 (7), 1183-1194, 2010
Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemia
B Xu, DM On, A Ma, T Parton, KD Konze, SG Pattenden, DF Allison, L Cai, ...
Blood, The Journal of the American Society of Hematology 125 (2), 346-357, 2015
The language of chromatin modification in human cancers
S Zhao, CD Allis, GG Wang
Nature Reviews Cancer 21 (7), 413-430, 2021
Bmi1 is a key epigenetic barrier to direct cardiac reprogramming
Y Zhou, L Wang, HR Vaseghi, Z Liu, R Lu, S Alimohamadi, C Yin, JD Fu, ...
Cell stem cell 18 (3), 382-395, 2016
Tudor: a versatile family of histone methylation ‘readers’
R Lu, GG Wang
Trends in biochemical sciences 38 (11), 546-555, 2013
Lens epithelium-derived growth factor fusion proteins redirect HIV-1 DNA integration
AL Ferris, X Wu, CM Hughes, C Stewart, SJ Smith, TA Milne, GG Wang, ...
Proceedings of the National Academy of Sciences 107 (7), 3135-3140, 2010
Epigenetic perturbations by Arg882-mutated DNMT3A potentiate aberrant stem cell gene-expression program and acute leukemia development
R Lu, P Wang, T Parton, Y Zhou, K Chrysovergis, S Rockowitz, WY Chen, ...
Cancer cell 30 (1), 92-107, 2016
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