Samuel J Keeney
Samuel J Keeney
Children's Hospital of Philadelphia, Penn Medicine
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Serotonin receptor 2B signaling with interstitial cell activation and leaflet remodeling in degenerative mitral regurgitation
KH Driesbaugh, E Branchetti, JB Grau, SJ Keeney, K Glass, MA Oyama, ...
Journal of molecular and cellular cardiology 115, 94-103, 2018
Glycation and serum albumin infiltration contribute to the structural degeneration of bioprosthetic heart valves
A Frasca, Y Xue, AP Kossar, S Keeney, C Rock, A Zakharchenko, ...
Basic to Translational Science 5 (8), 755-766, 2020
Model studies of advanced glycation end product modification of heterograft biomaterials: The effects of in vitro glucose, glyoxal, and serum albumin on collagen structure and …
CA Rock, S Keeney, A Zakharchenko, H Takano, DA Spiegel, AM Krieger, ...
Acta Biomaterialia 123, 275-285, 2021
Deterioration of Glutaraldehyde Crosslinked Heterograft Biomaterials due to Advanced Glycation End Product Formation and Serum Albumin Infiltration
CA Rock, S Keeney, A Zakharchenko, H Takano, DA Spiegel, AM Krieger, ...
bioRxiv, 2020
Inhibition and down regulation of the serotonin transporter contribute to the progression of degenerative mitral regurgitation
RJ Levy, E Fitzpatrick, E Castillero, HJ Shukla, VV Inamdar, AE Aghali, ...
bioRxiv, 2020
Serotonin Related Gene Expression Patterns in Aortic Valve Interstitial Cells Are Altered by Proliferation and Serotonin Transporter Inhibition
A Aghali, SJ Keeney, EG Fitzpatrick, H Shukla, E Castillero, I Fishbein, ...
Circulation 140 (Suppl_1), A15914-A15914, 2019
Accumulation of Advanced Glycation End Products Results in Inflammation-Mediated Structural Degeneration of Bioprosthetic Heart Valves
A Zakharchenko, S Keeney, SJ Stachelek, G Ferrari, H Takano, R Levy
Circulation 140 (Suppl_1), A14543-A14543, 2019
Advanced Glycation End Products Formation Drives Structural Bioprosthetic Valve Degeneration
Y Xue, A Frasca, S Keeney, A Zakharchenko, A Kossar, R Levy, G Ferrari
Circulation 140 (Suppl_1), A13508-A13508, 2019
Advanced Glycation End Products and the Pathophysiology of Bioprosthetic Heart Valve Structural Degeneration
A Frasca, S Keeney, S Lee, JE Bavaria, RC Gorman, RJ Levy, G Ferrari
Circulation 138 (Suppl_1), A16744-A16744, 2018
Mechanobiology of heart valves
L Hall, C Rock, A Frasca, S Keeney, G Ferrari, R Levy
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