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Samuel J Keeney
Samuel J Keeney
Children's Hospital of Philadelphia, Penn Medicine
Verified email at email.chop.edu
Title
Cited by
Cited by
Year
Serotonin receptor 2B signaling with interstitial cell activation and leaflet remodeling in degenerative mitral regurgitation
KH Driesbaugh, E Branchetti, JB Grau, SJ Keeney, K Glass, MA Oyama, ...
Journal of molecular and cellular cardiology 115, 94-103, 2018
332018
Iron imaging in myocardial infarction reperfusion injury
BF Moon, SK Iyer, E Hwuang, MP Solomon, AT Hall, R Kumar, ...
Nature communications 11 (1), 3273, 2020
312020
Glycation and serum albumin infiltration contribute to the structural degeneration of bioprosthetic heart valves
A Frasca, Y Xue, AP Kossar, S Keeney, C Rock, A Zakharchenko, ...
Basic to Translational Science 5 (8), 755-766, 2020
262020
Poly-2-methyl-2-oxazoline–modified bioprosthetic heart valve leaflets have enhanced biocompatibility and resist structural degeneration
A Zakharchenko, Y Xue, S Keeney, CA Rock, IS Alferiev, SJ Stachelek, ...
Proceedings of the National Academy of Sciences 119 (6), e2120694119, 2022
62022
Magnetic susceptibility and R2* of myocardial reperfusion injury at 3T and 7T
BF Moon, SK Iyer, NJ Josselyn, E Hwuang, S Swago, SJ Keeney, ...
Magnetic resonance in medicine 87 (1), 323-336, 2022
62022
Model studies of advanced glycation end product modification of heterograft biomaterials: The effects of in vitro glucose, glyoxal, and serum albumin on collagen structure and …
CA Rock, S Keeney, A Zakharchenko, H Takano, DA Spiegel, AM Krieger, ...
Acta biomaterialia 123, 275-285, 2021
62021
Decreased serotonin transporter activity in the mitral valve contributes to progression of degenerative mitral regurgitation
E Castillero, E Fitzpatrick, SJ Keeney, AM D’Angelo, BB Pressly, ...
Science translational medicine 15 (677), eadc9606, 2023
52023
Inhibition of advanced glycation end product formation and serum protein infiltration in bioprosthetic heart valve leaflets: Investigations of anti-glycation agents and …
A Zakharchenko, CA Rock, TE Thomas, S Keeney, EJ Hall, H Takano, ...
Biomaterials 289, 121782, 2022
52022
Altered responsiveness to tgfβ and bmp and increased cd45+ cell presence in mitral valves are unique features of ischemic mitral regurgitation
E Castillero, DP Howsmon, BV Rego, SJ Keeney, KH Driesbaugh, ...
Arteriosclerosis, thrombosis, and vascular biology 41 (6), 2049-2062, 2021
32021
Inhibition and down regulation of the serotonin transporter contribute to the progression of degenerative mitral regurgitation
RJ Levy, E Fitzpatrick, E Castillero, HJ Shukla, VV Inamdar, AE Aghali, ...
bioRxiv, 2020.03. 10.985382, 2020
12020
Accumulation of Advanced Glycation End Products Results in Inflammation-Mediated Structural Degeneration of Bioprosthetic Heart Valves
A Zakharchenko, S Keeney, SJ Stachelek, G Ferrari, H Takano, R Levy
Circulation 140 (Suppl_1), A14543-A14543, 2019
12019
Inhibition of Advanced Glycation End Products Formation and Serum Protein Infiltration in Bioprosthetic Heart Valves: Investigations of Anti-Glycation Agents
A Zakharchenko, CA Rock, T Thomas, S Keeney, EJ Hall, H Takano, ...
Circulation 146 (Suppl_1), A13187-A13187, 2022
2022
Polyoxazoline Modification of Bovine Pericardial Bioprosthetic Heart Valve Leaflets Mitigates Protein-Glycation Associated Structural Degeneration
A Zakharchenko, S Keeney, IS Alferiev, M Chorny, Y Xue, H Takano, ...
Circulation 144 (Suppl_1), A13818-A13818, 2021
2021
Deterioration of Glutaraldehyde Crosslinked Heterograft Biomaterials due to Advanced Glycation End Product Formation and Serum Albumin Infiltration
CA Rock, S Keeney, A Zakharchenko, H Takano, DA Spiegel, AM Krieger, ...
bioRxiv, 2020.05. 28.117739, 2020
2020
Serotonin Related Gene Expression Patterns in Aortic Valve Interstitial Cells Are Altered by Proliferation and Serotonin Transporter Inhibition
A Aghali, SJ Keeney, EG Fitzpatrick, H Shukla, E Castillero, I Fishbein, ...
Circulation 140 (Suppl_1), A15914-A15914, 2019
2019
Advanced Glycation End Products Formation Drives Structural Bioprosthetic Valve Degeneration
Y Xue, A Frasca, S Keeney, A Zakharchenko, A Kossar, R Levy, G Ferrari
Circulation 140 (Suppl_1), A13508-A13508, 2019
2019
Advanced Glycation End Products and the Pathophysiology of Bioprosthetic Heart Valve Structural Degeneration
A Frasca, S Keeney, S Lee, JE Bavaria, RC Gorman, RJ Levy, G Ferrari
Circulation 138 (Suppl_1), A16744-A16744, 2018
2018
Magnetic susceptibility, R2* and iron evolve during reperfusion injury wound healing
BF Moon, SK Iyer, E Hwuang, NJ Josselyn, JJ Pilla, JH Gorman III, ...
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