| Study on the binding of Thioflavin T to β-sheet-rich and non-β-sheet cavities M Groenning, L Olsen, M van de Weert, JM Flink, S Frokjaer, ... Journal of structural biology 158 (3), 358-369, 2007 | 246 | 2007 |
| GABAA receptor agonists, partial agonists, and antagonists. Design and therapeutic prospects P Krogsgaard-Larsen, B Froelund, FS Joergensen, A Schousboe Journal of medicinal chemistry 37 (16), 2489-2505, 1994 | 128 | 1994 |
| Evaluation and comparison of 3D-QSAR CoMSIA models for CDK1, CDK5, and GSK-3 inhibition by paullones C Kunick, K Lauenroth, K Wieking, X Xie, C Schultz, R Gussio, ... Journal of Medicinal Chemistry 47 (1), 22-36, 2004 | 126 | 2004 |
| Prediction methods and databases within chemoinformatics: emphasis on drugs and drug candidates SÓ Jónsdóttir, FS Jørgensen, S Brunak Bioinformatics 21 (10), 2145-2160, 2005 | 125 | 2005 |
| A new concept for multidimensional selection of ligand conformations (MultiSelect) and multidimensional scoring (MultiScore) of protein− ligand binding affinities GE Terp, BN Johansen, IT Christensen, FS Jørgensen Journal of medicinal chemistry 44 (14), 2333-2343, 2001 | 118 | 2001 |
| Mutational mapping and modeling of the binding site for (S)-citalopram in the human serotonin transporter J Andersen, L Olsen, KB Hansen, O Taboureau, FS Jørgensen, ... Journal of Biological Chemistry 285 (3), 2051-2063, 2010 | 99 | 2010 |
| Classification of cytochrome P450 1A2 inhibitors and noninhibitors by machine learning techniques P Vasanthanathan, O Taboureau, C Oostenbrink, NPE Vermeulen, ... Drug Metabolism and Disposition 37 (3), 658-664, 2009 | 98 | 2009 |
| hERG classification model based on a combination of support vector machine method and GRIND descriptors Q Li, FS Jørgensen, T Oprea, S Brunak, O Taboureau Molecular pharmaceutics 5 (1), 117-127, 2008 | 96 | 2008 |
| Structural differences of matrix metalloproteinases with potential implications for inhibitor selectivity examined by the GRID/CPCA approach GE Terp, G Cruciani, IT Christensen, FS Jørgensen Journal of medicinal chemistry 45 (13), 2675-2684, 2002 | 96 | 2002 |
| Identification of a gene on chromosome 12q22 uniquely overexpressed in chronic lymphocytic leukemia AM Buhl, J Jurlander, FS Jørgensen, AM Ottesen, JB Cowland, ... Blood 107 (7), 2904-2911, 2006 | 89 | 2006 |
| Prediction of pH-dependent aqueous solubility of druglike molecules NT Hansen, I Kouskoumvekaki, FS Jørgensen, S Brunak, SO Jonsdottir Journal of chemical information and modeling 46 (6), 2601-2609, 2006 | 84 | 2006 |
| Prediction of cytochrome P450 mediated metabolism L Olsen, C Oostenbrink, FS Jørgensen Advanced drug delivery reviews 86, 61-71, 2015 | 79 | 2015 |
| Virtual screening and prediction of site of metabolism for cytochrome P450 1A2 ligands P Vasanthanathan, J Hritz, O Taboureau, L Olsen, F Steen Jørgensen, ... Journal of chemical information and modeling 49 (1), 43-52, 2009 | 77 | 2009 |
| Recent advances in GABA agonists, antagonists and uptake inhibitors: structure–activity relationships and therapeutic potential P KROGSGAARD-LARSEN, H HJEDS, E FALCH, FS JØRGENSEN, ... Advances in drug research 17, 381-456, 1988 | 68 | 1988 |
| Cyclynes. Part 5. Pericyclynes:" exploded cycloalkanes" with unusual orbital interactions and conformational properties. MM2 and STO-3G calculations, x-ray crystal structures … KN Houk, LT Scott, NG Rondan, DC Spellmeyer, G Reinhardt, JL Hyun, ... Journal of the American Chemical Society 107 (23), 6556-6562, 1985 | 59 | 1985 |
| Solvent diversity in polymorph screening M Allesø, F Van Den Berg, C Cornett, FS Jørgensen, B Halling-Sørensen, ... Journal of pharmaceutical sciences 97 (6), 2145-2159, 2008 | 56 | 2008 |
| New leads of metallo-β-lactamase inhibitors from structure-based pharmacophore design L Olsen, S Jost, HW Adolph, I Pettersson, L Hemmingsen, FS Jørgensen Bioorganic & medicinal chemistry 14 (8), 2627-2635, 2006 | 56 | 2006 |
| Towards an understanding of drug resistance in malaria: three-dimensional structure of Plasmodium falciparum dihydrofolate reductase by homology building T Lemcke, IT Christensen, FS Jørgensen Bioorganic & medicinal chemistry 7 (6), 1003-1011, 1999 | 56 | 1999 |
| Primary structure and conformational analysis of peptide methionine—tyrosine, a peptide related to neuropeptide Y and peptide YY isolated from lamprey intestine JM CONLON, B BJØRNHOLM, FS JØRGENSEN, JH YOUSON, ... European journal of biochemistry 199 (2), 293-298, 1991 | 56 | 1991 |
| Human peptide transporters: therapeutic applications CU Nielsen, B Brodin, FS Jørgensen, S Frokjaer, B Steffansen Expert Opinion on Therapeutic Patents 12 (9), 1329-1350, 2002 | 54 | 2002 |
Lars OlsenDepartment of Drug Design and Pharmacology, University of CopenhagenVerified email at novozymes.com
