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Amitabh Sharma
Amitabh Sharma
Assistant Professor of Medicine, Harvard Medical School
Verifierad e-postadress på channing.harvard.edu
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Uncovering disease-disease relationships through the incomplete interactome
J Menche, A Sharma, M Kitsak, SD Ghiassian, M Vidal, J Loscalzo, ...
Science 347 (6224), 1257601, 2015
11252015
A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses
S Ripatti, E Tikkanen, M Orho-Melander, AS Havulinna, K Silander, ...
The Lancet 376 (9750), 1393-1400, 2010
5972010
Human symptoms–disease network
XZ Zhou, J Menche, AL Barabási, A Sharma
Nature communications 5, 4212, 2014
5632014
Widespread macromolecular interaction perturbations in human genetic disorders
N Sahni, S Yi, M Taipale, JIF Bass, J Coulombe-Huntington, F Yang, ...
Cell 161 (3), 647-660, 2015
4362015
A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets
J Taneera, S Lang, A Sharma, J Fadista, Y Zhou, E Ahlqvist, A Jonsson, ...
Cell metabolism 16 (1), 122-134, 2012
3582012
Controllability analysis of the directed human protein interaction network identifies disease genes and drug targets
A Vinayagam, TE Gibson, HJ Lee, B Yilmazel, C Roesel, Y Hu, Y Kwon, ...
Proceedings of the National Academy of Sciences 113 (18), 4976-4981, 2016
2082016
Mining literature for a comprehensive pathway analysis: a case study for retrieval of homocysteine related genes for genetic and epigenetic studies
P Sharma, RD Senthilkumar, V Brahmachari, E Sundaramoorthy, ...
Lipids in health and disease 5 (1), 1, 2006
1892006
Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21
R Tabassum, G Chauhan, OP Dwivedi, A Mahajan, A Jaiswal, I Kaur, ...
Diabetes 62 (3), 977-986, 2013
1862013
Early pregnancy vitamin D status and risk of preeclampsia
H Mirzakhani, AA Litonjua, TF McElrath, G O’Connor, A Lee-Parritz, ...
The Journal of clinical investigation 126 (12), 4702-4715, 2016
1772016
PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation
H Iwata, C Goettsch, A Sharma, P Ricchiuto, WWB Goh, A Halu, I Yamada, ...
Nature communications 7, 12849, 2016
1752016
A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma
A Sharma, J Menche, CC Huang, T Ort, X Zhou, M Kitsak, N Sahni, ...
Human molecular genetics 24 (11), 3005-3020, 2015
1672015
Network Medicine in the age of biomedical big data
AR Sonawane, ST Weiss, K Glass, A Sharma
Frontiers in Genetics 10, 2019
1122019
Uremic toxin indoxyl sulfate promotes proinflammatory macrophage activation via the interplay of OATP2B1 and Dll4-Notch signaling: potential mechanism for accelerated …
T Nakano, S Katsuki, M Chen, JL Decano, A Halu, LH Lee, DVS Pestana, ...
Circulation 139 (1), 78-96, 2019
1042019
Tissue specificity of human disease module
M Kitsak, A Sharma, J Menche, E Guney, SD Ghiassian, J Loscalzo, ...
Scientific reports 6, 35241, 2016
922016
The multiplex network of human diseases
A Halu, M De Domenico, A Arenas, A Sharma
NPJ systems biology and applications 5 (1), 15, 2019
742019
Endophenotype network models: common core of complex diseases
SD Ghiassian, J Menche, DI Chasman, F Giulianini, R Wang, P Ricchiuto, ...
Scientific reports 6, 27414, 2016
692016
Degradation assessment of low density polythene (LDP) and polythene (PP) by an indigenous isolate of Pseudomonas stutzeri
A Sharma, A Sharma
CSIR, 2004
412004
A systems approach to refine disease taxonomy by integrating phenotypic and molecular networks
X Zhou, L Lei, J Liu, A Halu, Y Zhang, B Li, Z Guo, G Liu, C Sun, ...
EBioMedicine 31, 79-91, 2018
382018
Network-based analysis of genome wide association data provides novel candidate genes for lipid and lipoprotein traits
A Sharma, N Gulbahce, SJ Pevzner, J Menche, C Ladenvall, L Folkersen, ...
Molecular & Cellular Proteomics 12 (11), 3398-3408, 2013
362013
Integration of molecular interactome and targeted interaction analysis to identify a COPD disease network module
A Sharma, M Kitsak, MH Cho, A Ameli, X Zhou, Z Jiang, JD Crapo, ...
Scientific reports 8 (1), 14439, 2018
342018
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Artiklar 1–20