| On the use of the O-methylmandelate ester for establishment of absolute configuration of secondary alcohols BM Trost, JL Belletire, S Godleski, PG McDougal, JM Balkovec, ... The Journal of Organic Chemistry 51 (12), 2370-2374, 1986 | 736 | 1986 |
| 11β-HSD1 inhibition ameliorates metabolic syndrome and prevents progression of atherosclerosis in mice A Hermanowski-Vosatka, JM Balkovec, K Cheng, HY Chen, M Hernandez, ... The Journal of Experimental Medicine 202 (4), 517-527, 2005 | 499 | 2005 |
| In vitro preclinical evaluation studies with the echinocandin antifungal MK-0991 (L-743,872) K Bartizal, CJ Gill, GK Abruzzo, AM Flattery, LI Kong, PM Scott, JG Smith, ... Antimicrobial agents and chemotherapy 41 (11), 2326-2332, 1997 | 383 | 1997 |
| The first stereoselective total synthesis of quinine G Stork, D Niu, A Fujimoto, ER Koft, JM Balkovec, JR Tata, GR Dake Journal of the American Chemical Society 123 (14), 3239-3242, 2001 | 311 | 2001 |
| Evaluation of the echinocandin antifungal MK-0991 (L-743,872): efficacies in mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis GK Abruzzo, AM Flattery, CJ Gill, L Kong, JG Smith, VB Pikounis, ... Antimicrobial agents and chemotherapy 41 (11), 2333-2338, 1997 | 296 | 1997 |
| Succinic acids as potent inhibitors of plasmid-borne IMP-1 metallo-β-lactamase JH Toney, GG Hammond, PMD Fitzgerald, N Sharma, JM Balkovec, ... Journal of Biological Chemistry 276 (34), 31913-31918, 2001 | 252 | 2001 |
| Elongation factor 2 as a novel target for selective inhibition of fungal protein synthesis MC Justice, MJ Hsu, B Tse, T Ku, J Balkovec, D Schmatz, J Nielsen Journal of Biological Chemistry 273 (6), 3148-3151, 1998 | 218 | 1998 |
| Efficacy of MK-991 (L-743,872), a Semisynthetic Pneumocandin, in Murine Models ofPneumocystis carinii MA Powles, P Liberator, J Anderson, Y Karkhanis, JF Dropinski, ... Antimicrobial Agents and Chemotherapy 42 (8), 1985-1989, 1998 | 186 | 1998 |
| Discovery and development of first in class antifungal caspofungin (CANCIDAS®)—A case study JM Balkovec, DL Hughes, PS Masurekar, CA Sable, RE Schwartz, ... Natural Product Reports 31 (1), 15-34, 2014 | 155 | 2014 |
| Adamantyl triazoles as selective inhibitors of 11β-hydroxysteroid dehydrogenase type 1 S Olson, SD Aster, K Brown, L Carbin, DW Graham, ... Bioorganic & medicinal chemistry letters 15 (19), 4359-4362, 2005 | 131 | 2005 |
| Synthesis and antifungal activity of novel cationic pneumocandin Bo derivatives FA Bouffard, RA Zambias, JF Dropinski, JM Balkovec, ML Hammond, ... Journal of medicinal chemistry 37 (2), 222-225, 1994 | 129 | 1994 |
| A total synthesis of plumericin, allamcin and allamandin. Part 2. A biomimetic strategy BM Trost, JM Balkovec, MKT Mao Journal of the American Chemical Society 108 (16), 4974-4983, 1986 | 127* | 1986 |
| Christy,. E.; Ponticello, GS; Varga, S. L BM Trost, JL Belletire, S Godleski, PG McDougal, JM Balkovec, ... Springer, JP J. Org. Chem 51 (2370), 0002-7863, 1986 | 120 | 1986 |
| In vitro antifungal activities and in vivo efficacies of 1, 3-beta-D-glucan synthesis inhibitors L-671,329, L-646,991, tetrahydroechinocandin B, and L-687,781, a papulacandin K Bartizal, G Abruzzo, C Trainor, D Krupa, K Nollstadt, D Schmatz, ... Antimicrobial agents and chemotherapy 36 (8), 1648-1657, 1992 | 115 | 1992 |
| Attenuating pregnane X receptor (PXR) activation: a molecular modelling approach YD Gao, SH Olson, JM Balkovec, Y Zhu, I Royo, J Yabut, R Evers, EY Tan, ... Xenobiotica 37 (2), 124-138, 2007 | 114 | 2007 |
| Preclinical evaluation of the stability, safety, and efficacy of CD101, a novel echinocandin V Ong, G Hough, M Schlosser, K Bartizal, JM Balkovec, KD James, ... Antimicrobial agents and chemotherapy 60 (11), 6872-6879, 2016 | 107 | 2016 |
| Increased antifungal activity of L-733,560, a water-soluble, semisynthetic pneumocandin, is due to enhanced inhibition of cell wall synthesis MB Kurtz, C Douglas, J Marrinan, K Nollstadt, J Onishi, S Dreikorn, ... Antimicrobial agents and chemotherapy 38 (12), 2750-2757, 1994 | 93 | 1994 |
| Triazole derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1 ST Waddell, GM Santorelli, MM Maletic, AH Leeman, X Gu, DW Graham, ... US Patent 6,849,636, 2005 | 88 | 2005 |
| Novel N-Arylpyrazolo[3,2-c]-Based Ligands for the Glucocorticoid Receptor: Receptor Binding and in Vivo Activity A Ali, CF Thompson, JM Balkovec, DW Graham, ML Hammond, ... Journal of medicinal chemistry 47 (10), 2441-2452, 2004 | 87 | 2004 |
| Synthesis and SAR of thioester and thiol inhibitors of IMP-1 metallo-β-lactamase ML Greenlee, JB Laub, JM Balkovec, ML Hammond, GG Hammond, ... Bioorganic & medicinal chemistry letters 9 (17), 2549-2554, 1999 | 87 | 1999 |
