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Homa Ghalei
Homa Ghalei
Associate Professor of Biochemistry, Emory University
Verifierad e-postadress på emory.edu - Startsida
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Rps26 directs mRNA-specific translation by recognition of Kozak sequence elements
MB Ferretti, H Ghalei, EA Ward, EL Potts, K Karbstein
Nature structural & molecular biology 24 (9), 700-707, 2017
1302017
Hrr25/CK1δ-directed release of Ltv1 from pre-40S ribosomes is necessary for ribosome assembly and cell growth
H Ghalei, FX Schaub, JR Doherty, Y Noguchi, WR Roush, JL Cleveland, ...
Journal of Cell Biology 208 (6), 745-759, 2015
972015
Structural heterogeneity in pre-40S ribosomes
MC Johnson, H Ghalei, KA Doxtader, K Karbstein, ME Stroupe
Structure 25 (2), 329-340, 2017
722017
The ATPase Fap7 tests the ability to carry out translocation-like conformational changes and releases Dim1 during 40S ribosome maturation
H Ghalei, J Trepreau, JC Collins, H Bhaskaran, BS Strunk, K Karbstein
Molecular cell 67 (6), 990-1000. e3, 2017
612017
Ribosome biogenesis factor Ltv1 chaperones the assembly of the small subunit head
JC Collins, H Ghalei, JR Doherty, H Huang, RN Culver, K Karbstein
Journal of Cell Biology 217 (12), 4141-4154, 2018
452018
A kinase-dependent checkpoint prevents escape of immature ribosomes into the translating pool
MD Parker, JC Collins, B Korona, H Ghalei, K Karbstein
PLoS biology 17 (12), e3000329, 2019
312019
Ribosomal RNA 2′-O-methylations regulate translation by impacting ribosome dynamics
S Khoshnevis, RE Dreggors-Walker, V Marchand, Y Motorin, H Ghalei
Proceedings of the National Academy of Sciences 119 (12), e2117334119, 2022
302022
A novel Nop5–sRNA interaction that is required for efficient archaeal box C/D sRNP formation
H Ghalei, HH Hsiao, H Urlaub, MC Wahl, NJ Watkins
Rna 16 (12), 2341-2348, 2010
222010
Quality control of 40S ribosome head assembly ensures scanning competence
H Huang, H Ghalei, K Karbstein
Journal of Cell Biology 219 (11), e202004161, 2020
212020
Structural basis for the dual U4 and U4atac snRNA-binding specificity of spliceosomal protein hPrp31
S Liu, H Ghalei, R Lührmann, MC Wahl
RNA 17 (9), 1655-1663, 2011
202011
An open interface in the pre-80S ribosome coordinated by ribosome assembly factors Tsr1 and Dim1 enables temporal regulation of Fap7
J Rai, MD Parker, H Huang, S Choy, H Ghalei, MC Johnson, K Karbstein, ...
Rna 27 (2), 221-233, 2021
182021
Entrapment of DNA in an intersubunit tunnel system of a single-stranded DNA-binding protein
H Ghalei, H Moeller, D Eppers, D Sohmen, DN Wilson, B Loll, MC Wahl
Nucleic Acids Research 42 (10), 6698-6708, 2014
172014
Phosphorylation regulates arginine-rich RNA-binding protein solubility and oligomerization
SR Kundinger, EB Dammer, L Yin, C Hurst, S Shapley, L Ping, ...
Journal of Biological Chemistry 297 (5), 2021
112021
A conserved Bcd1 interaction essential for box C/D snoRNP biogenesis
S Khoshnevis, RE Dreggors, TFR Hoffmann, H Ghalei
Journal of Biological Chemistry 294 (48), 18360-18371, 2019
112019
Practical advice for mentoring and supporting faculty colleagues in STEM fields: Views from mentor and mentee perspectives
JM Spangle, H Ghalei, AH Corbett
Journal of Biological Chemistry 297 (3), 2021
72021
Studies of mutations of assembly factor Hit1 in budding yeast suggest translation defects as the molecular basis for PEHO syndrome
RE Dreggors-Walker, LN Cohen, S Khoshnevis, V Marchand, Y Motorin, ...
Journal of Biological Chemistry 298 (9), 2022
32022
Subunit joining exposes nascent pre-40S rRNA for processing and quality control
J Rai, MD Parker, H Ghalei, MC Johnson, K Karbstein, ME Stroupe
bioRxiv, 2019
32019
Comparative analyses of disease-linked missense mutations in the RNA exosome modeled in budding yeast reveal distinct functional consequences in translation
MC Sterrett, LA Cureton, LN Cohen, A van Hoof, S Khoshnevis, ...
bioRxiv, 2023
12023
RNA structural probing of guanine and uracil nucleotides in yeast
K Xiao, H Ghalei, S Khoshnevis
Plos one 18 (7), e0288070, 2023
12023
The RNA helicase DDX1 associates with the nuclear RNA exosome and modulates R-loops
JL de Amorim, SW Leung, R Haji-Seyed-Javadi, Y Hou, DS Yu, H Ghalei, ...
bioRxiv, 2023.04. 17.537228, 2023
12023
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Artiklar 1–20