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Kendall J. Condon
Kendall J. Condon
Graduate Student, MIT
Verifierad e-postadress på MIT.edu
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SAMTOR is an S-adenosylmethionine sensor for the mTORC1 pathway
X Gu, JM Orozco, RA Saxton, KJ Condon, GY Liu, PA Krawczyk, ...
Science 358 (6364), 813-818, 2017
4742017
Structural basis for gating and activation of RyR1
A des Georges, OB Clarke, R Zalk, Q Yuan, KJ Condon, RA Grassucci, ...
Cell 167 (1), 145-157. e17, 2016
3702016
Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors
SM Davidson, O Jonas, MA Keibler, HW Hou, A Luengo, JR Mayers, ...
Nature medicine 23 (2), 235-241, 2017
2992017
Nutrient regulation of mTORC1 at a glance
KJ Condon, DM Sabatini
Journal of cell science 132 (21), jcs222570, 2019
2972019
KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1
RL Wolfson, L Chantranupong, GA Wyant, X Gu, JM Orozco, K Shen, ...
Nature 543 (7645), 438-442, 2017
2942017
Architecture of the human GATOR1 and GATOR1–Rag GTPases complexes
K Shen, RK Huang, EJ Brignole, KJ Condon, ML Valenstein, ...
Nature 556 (7699), 64-69, 2018
1592018
Fumarate is a terminal electron acceptor in the mammalian electron transport chain
JB Spinelli, PC Rosen, HG Sprenger, AM Puszynska, JL Mann, ...
Science 374 (6572), 1227-1237, 2021
1172021
Genome-wide CRISPR screens reveal multitiered mechanisms through which mTORC1 senses mitochondrial dysfunction
KJ Condon, JM Orozco, CH Adelmann, JB Spinelli, PW van der Helm, ...
Proceedings of the National Academy of Sciences 118 (4), e2022120118, 2021
772021
Autoinhibitory interdomain interactions and subfamily-specific extensions redefine the catalytic core of the human DEAD-box protein DDX3
SN Floor, KJ Condon, D Sharma, E Jankowsky, JA Doudna
Journal of Biological Chemistry 291 (5), 2412-2421, 2016
772016
MFSD12 mediates the import of cysteine into melanosomes and lysosomes
CH Adelmann, AK Traunbauer, B Chen, KJ Condon, SH Chan, T Kunchok, ...
Nature 588 (7839), 699-704, 2020
612020
Analog sensitive chemical inhibition of the DEAD‐box protein DDX 3
SN Floor, KJ Barkovich, KJ Condon, KM Shokat, JA Doudna
Protein Science 25 (3), 638-649, 2016
192016
A systematic approach for cataloging mTORC1 regulators
KJ Condon
Massachusetts Institute of Technology, 2021
2021
Functional study of the ryanodine receptor type 1 using cryo-electron microscopy
A des Georges, OB Clarke, R Zalk, Q Yuan, KJ Condon, RA Grassucci, ...
Biophysical Journal 112 (3), 335a, 2017
2017
Engineering Inhibitor Specificity in the Dead-Box Protein Family
K Condon, S Floor, J Doudna
Biophysical Journal 106 (2), 495a-496a, 2014
2014
Paper f Paper f
SM Chan, RH Chandler, RW Chapman, EK Chen, T Chen, HY Cheng, ...
mTORC1 binds RHEB: GTP
KJ Condon, B May, DM Sabatini
BMT2 (SAMTOR) binds S-adenosylme-thionine and dissociates from KIC-STOR: GATOR1
KJ Condon, B May, DM Sabatini
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Artiklar 1–17