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Xiangnan Guan
Xiangnan Guan
Verifierad e-postadress på gene.com
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Androgen receptor activity in T cells limits checkpoint blockade efficacy
X Guan*, F Polesso* (co-first), C Wang* (co-first), A Sehrawat, ...
Nature, 1-6, 2022
1882022
Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing data
D Sun, X Guan, AE Moran, LY Wu, DZ Qian, P Schedin, MS Dai, ...
Nature biotechnology 40 (4), 527-538, 2022
1482022
Genomic drivers of poor prognosis and enzalutamide resistance in metastatic castration-resistant prostate cancer
WS Chen, R Aggarwal, L Zhang, SG Zhao, GV Thomas, TM Beer, ...
European urology 76 (5), 562-571, 2019
1242019
Transcriptional profiling identifies an androgen receptor activity-low, stemness program associated with enzalutamide resistance
JJ Alumkal, D Sun, E Lu, TM Beer, GV Thomas, E Latour, R Aggarwal, ...
Proceedings of the National Academy of Sciences 117 (22), 12315-12323, 2020
982020
Stromal senescence by prolonged CDK4/6 inhibition potentiates tumor growth
X Guan, KM LaPak, RC Hennessey, YY Christina, R Shakya, J Zhang, ...
Molecular Cancer Research, molcanres. 0319.2016, 2016
852016
BET bromodomain inhibition blocks an AR-repressed, E2F1-activated treatment-emergent neuroendocrine prostate cancer lineage plasticity program
DH Kim, D Sun, WK Storck, K Welker Leng, C Jenkins, DJ Coleman, ...
Clinical Cancer Research 27 (17), 4923-4936, 2021
432021
T cell transcriptional profiling and immunophenotyping uncover LAG3 as a potential significant target of immune modulation in multiple myeloma
F Lucas, M Pennell, Y Huang, DM Benson, YA Efebera, M Chaudhry, ...
Biology of Blood and Marrow Transplantation 26 (1), 7-15, 2020
432020
Wheat hypersensitive-induced reaction genes TaHIR1 and TaHIR3 are involved in response to stripe rust fungus infection and abiotic stresses
Y Duan, J Guo, X Shi, X Guan, F Liu, P Bai, L Huang, Z Kang
Plant cell reports 32, 273-283, 2013
422013
Biocontrol efficiency of Meyerozyma guilliermondii Y-1 against apple postharvest decay caused by Botryosphaeria dothidea and the possible mechanisms of action
Y Huang, C Sun, X Guan, S Lian, B Li, C Wang
International Journal of Food Microbiology 338, 108957, 2021
372021
The ectonucleotidase CD39 identifies tumor-reactive CD8+ T cells predictive of immune checkpoint blockade efficacy in human lung cancer
A Chow, FZ Uddin, M Liu, A Dobrin, BY Nabet, L Mangarin, Y Lavin, ...
Immunity 56 (1), 93-106. e6, 2023
292023
Butylated Hydroxytoluene Induced Resistance Against Botryosphaeria dothidea in Apple Fruit
Y Huang, C Sun, X Guan, S Lian, B Li, C Wang
Frontiers in Microbiology 11, 599062, 2021
242021
Pregnancy and weaning regulate human maternal liver size and function
A Q. Bartlett, KK Vesco, JQ Purnell, M Francisco, E Goddard, X Guan, ...
Proceedings of the National Academy of Sciences 118 (48), e2107269118, 2021
232021
Transcriptional profiling of matched patient biopsies clarifies molecular determinants of enzalutamide-induced lineage plasticity
TC Westbrook*, X Guan* (co-first), E Rodansky, D Flores, CJ Liu, ...
Nature Communications 13 (1), 1-13, 2022
162022
A distinct innate immune signature of early onset colorectal cancer
IH Gardner, R Siddharthan, K Watson, E Dewey, R Ruhl, S Khou, X Guan, ...
Immunohorizons 5 (6), 489-499, 2021
162021
Increased nuclear but not cytoplasmic activities of CELF1 protein leads to muscle wasting
DC Cox, X Guan, Z Xia, TA Cooper
Human molecular genetics 29 (10), 1729-1744, 2020
162020
658MO Cisplatin (cis)-related immunomodulation and efficacy with atezolizumab (atezo)+ cis-vs carboplatin (carbo)-based chemotherapy (chemo) in metastatic urothelial cancer (mUC)
MD Galsky, X Guan, R Banchereau, L Wang, J Zhu, H Yu, D Rishipathak, ...
Annals of Oncology 32, S682-S683, 2021
152021
Agrobacterium tumefaciens-mediated transformation of Valsa mali: an efficient tool for random insertion mutagenesis
C Wang, X Guan, H Wang, G Li, X Dong, G Wang, B Li
The Scientific World Journal 2013, 2013
142013
Reversible cardiac disease features in an inducible CUG repeat RNA–expressing mouse model of myotonic dystrophy
AN Rao, HM Campbell, X Guan, TA Word, XHT Wehrens, Z Xia, ...
JCI insight 6 (5), 2021
132021
Single-cell analysis reveals clonally expanded tumor-associated CD57+ CD8 T cells are enriched in the periphery of patients with metastatic urothelial cancer responding to PD …
M Fehlings, L Kim, X Guan, K Yuen, A Tafazzol, S Sanjabi, OA Zill, ...
Journal for Immunotherapy of Cancer 10 (8), 2022
122022
A type I MADS-box gene is differentially expressed in wheat in response to infection by the stripe rust fungus
J Guo, XX Shi, JS Zhang, YH Duan, PF Bai, XN Guan, ZS Kang
Biologia plantarum 57, 540-546, 2013
122013
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Artiklar 1–20