Common and potentially prebiotic origin for precursors of nucleotide synthesis and activation AC Fahrenbach, C Giurgiu, CP Tam, L Li, Y Hongo, M Aono, JW Szostak Journal of the American Chemical Society 139 (26), 8780-8783, 2017 | 85 | 2017 |
Non-enzymatic primer extension with strand displacement L Zhou, SC Kim, KH Ho, DK O'Flaherty, C Giurgiu, TH Wright, JW Szostak Elife 8, e51888, 2019 | 47 | 2019 |
The emergence of RNA from the heterogeneous products of prebiotic nucleotide synthesis SC Kim, DK O’Flaherty, C Giurgiu, L Zhou, JW Szostak Journal of the American Chemical Society 143 (9), 3267-3279, 2021 | 26 | 2021 |
A mechanistic explanation for the regioselectivity of nonenzymatic RNA primer extension C Giurgiu, L Li, DK O’Flaherty, CP Tam, JW Szostak Journal of the American Chemical Society 139 (46), 16741-16747, 2017 | 23 | 2017 |
Kinetic explanations for the sequence biases observed in the nonenzymatic copying of RNA templates D Ding, L Zhou, C Giurgiu, JW Szostak Nucleic Acids Research 50 (1), 35-45, 2022 | 22 | 2022 |
Prebiotically plausible “patching” of RNA backbone cleavage through a 3′–5′ pyrophosphate linkage TH Wright, C Giurgiu, W Zhang, A Radakovic, DK O’Flaherty, L Zhou, ... Journal of the American Chemical Society 141 (45), 18104-18112, 2019 | 20 | 2019 |
A Fluorescent G‐Quadruplex Sensor for Chemical RNA Copying C Giurgiu, TH Wright, DK O'Flaherty, JW Szostak Angewandte Chemie International Edition 57 (31), 9844-9848, 2018 | 13 | 2018 |
Structure–Activity Relationships in Nonenzymatic Template‐Directed RNA Synthesis C Giurgiu, Z Fang, HRM Aitken, SC Kim, L Pazienza, S Mittal, JW Szostak Angewandte Chemie International Edition 60 (42), 22925-22932, 2021 | 11 | 2021 |
Investigating the Mechanism of Non-Enzymatic RNA Replication C Giurgiu Harvard University, 2021 | | 2021 |
Supporting information A Mechanistic Explanation for the Regioselectivity of Nonenzymatic RNA Primer Extension C Giurgiu, L Li, DK O’Flaherty, CP Tam, JW Szostak | | |