| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13130* | 2021 |
| mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events MK Holz, BA Ballif, SP Gygi, J Blenis Cell 123 (4), 569-580, 2005 | 1457 | 2005 |
| RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation PP Roux, D Shahbazian, H Vu, MK Holz, MS Cohen, J Taunton, ... Journal of Biological Chemistry 282 (19), 14056-14064, 2007 | 869 | 2007 |
| The therapeutic potential of resveratrol: a review of clinical trials AY Berman, RA Motechin, MY Wiesenfeld, MK Holz NPJ precision oncology 1 (1), 35, 2017 | 748 | 2017 |
| Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase MK Holz, J Blenis Journal of Biological Chemistry 280 (28), 26089-26093, 2005 | 444 | 2005 |
| S6 kinase 1 regulates estrogen receptor α in control of breast cancer cell proliferation RL Yamnik, A Digilova, DC Davis, ZN Brodt, CJ Murphy, MK Holz Journal of Biological Chemistry 284 (10), 6361-6369, 2009 | 300 | 2009 |
| mTOR/S6K1 and MAPK/RSK signaling pathways coordinately regulate estrogen receptor α serine 167 phosphorylation RL Yamnik, MK Holz FEBS letters 584 (1), 124-128, 2010 | 189 | 2010 |
| mTOR signaling for biological control and cancer A Alayev, MK Holz Journal of cellular physiology 228 (8), 1658-1664, 2013 | 177 | 2013 |
| The combination of rapamycin and resveratrol blocks autophagy and induces apoptosis in breast cancer cells A Alayev, SM Berger, MY Kramer, NS Schwartz, MK Holz Journal of cellular biochemistry 116 (3), 450-457, 2015 | 113 | 2015 |
| Tamoxifen action in ER-negative breast cancer S Manna, MK Holz Signal transduction insights 5, STI. S29901, 2016 | 105 | 2016 |
| mTORC1 directly phosphorylates and activates ERα upon estrogen stimulation A Alayev, RS Salamon, SM Berger, NS Schwartz, R Cuesta, RB Snyder, ... Oncogene 35 (27), 3535-3543, 2016 | 88 | 2016 |
| The role of S6K1 in ER-positive breast cancer MK Holz Cell cycle 11 (17), 3159-3165, 2012 | 76 | 2012 |
| Estrogenic regulation of S6K1 expression creates a positive regulatory loop in control of breast cancer cell proliferation DM Maruani, TN Spiegel, EN Harris, AS Shachter, HA Unger, ... Oncogene 31 (49), 5073-5080, 2012 | 74 | 2012 |
| Combination of rapamycin and resveratrol for treatment of bladder cancer A Alayev, RS Salamon, NS Schwartz, AY Berman, SL Wiener, MK Holz Journal of cellular physiology 232 (2), 436-446, 2017 | 62 | 2017 |
| Resveratrol prevents rapamycin-induced upregulation of autophagy and selectively induces apoptosis in TSC2-deficient cells A Alayev, Y Sun, R Snyder, S Malka Berger, J Yu, M Holz Cell cycle 13 (3), 371-382, 2014 | 61 | 2014 |
| ERRα is a marker of tamoxifen response and survival in triple-negative breast cancer S Manna, J Bostner, Y Sun, LD Miller, A Alayev, NS Schwartz, E Lager, ... Clinical Cancer Research 22 (6), 1421-1431, 2016 | 55 | 2016 |
| Resveratrol as a novel treatment for diseases with mTOR pathway hyperactivation A Alayev, SM Berger, MK Holz Annals of the New York Academy of Sciences 1348 (1), 116-123, 2015 | 52 | 2015 |
| ERRα regulates the growth of triple-negative breast cancer cells via S6K1-dependent mechanism AY Berman, S Manna, NS Schwartz, YE Katz, Y Sun, CA Behrmann, JJ Yu, ... Signal transduction and targeted therapy 2 (1), 1-9, 2017 | 42 | 2017 |
| Phosphoproteomics reveals resveratrol-dependent inhibition of Akt/mTORC1/S6K1 signaling A Alayev, PF Doubleday, SM Berger, BA Ballif, MK Holz Journal of proteome research 13 (12), 5734-5742, 2014 | 40 | 2014 |
| RSK-mediated down-regulation of PDCD4 is required for proliferation, survival, and migration in a model of triple-negative breast cancer R Cuesta, MK Holz Oncotarget 7 (19), 27567, 2016 | 35 | 2016 |
